Serum AMH Levels in Patients Who Underwent Hypogastric Artery Ligation

AMH Clinical Trial

Official title:

Serum Antimullerian Hormone Levels in Patients Who Underwent Hypogastric Artery Ligation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03220594
• Other study ID #: 1826
• Status: Completed
• Phase: N/A
• First received: July 14, 2017
• Last updated: September 29, 2017
• Start date: March 20, 2017
• Est. completion date: September 29, 2017

Study information

• Verified date: September 2017
• Source: Kanuni Sultan Suleyman Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

To observe the effects of hypogastric artery ligation on serum antimullerian hormone levels.

Description:

To measure and compare serum antimullerian hormone levels in patients who underwent hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy and postpartum control. The procedures performed as an emergency life saving method during delivery. The reasons for hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy were obstetric hemorrhage mainly uterine atony.

The serum levels of antimullerian hormone were measured 6 months after the operations and compared with matching postpartum controls. Serum levels of FSH, LH, PRL and TSH were also measured 6 months after the operation. Further, antral follicle count measured along with the aforementioned blood tests.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 90
• Est. completion date: September 29, 2017
• Est. primary completion date: September 20, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• age 18- 40 years

• no systemic or endocrine diseases

• patients who had hypogastric artery ligation and/or hysterectomy

• healthy postpartum patients as controls

Exclusion Criteria:

• history of chemotherapy and/or radiotherapy

• Obese patients

• patients with previous/present endometriosis

• patients with PCOS

Related Conditions & MeSH terms

• AMH

Intervention

Procedure:
• hypogastric artery ligation
hypogastric artery ligation is the ligation of the internal iliac artery to stop bleeding related to obstetrics obstetric hemorrhage Hysterectomy is the removal of the uterus if bleeding can't stop by hypogastric artery ligation

Locations

Country	Name	City	State
Turkey	Kanuni SSTRH	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Kanuni Sultan Suleyman Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Ovarian reserve	To evaluate postoperative ovarian reserve using anti-mullerian hormones and other ovary related hormones including FSH,LH	6 months

External Links

•   Effect of internal iliac artery ligation on ovarian blood supply and ovarian reserve
•   The effect of total abdominal hysterectomy on serum anti-Müllerian hormone levels: a pilot study