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Amblyopia clinical trials

View clinical trials related to Amblyopia.

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NCT ID: NCT06049459 Recruiting - Amblyopia Clinical Trials

Novel Amblyopia Treatment With Virtual Reality Games

Start date: March 14, 2024
Phase: N/A
Study type: Interventional

The goal of this study is to compare the change in amblyopic eye acuity between treatment periods in children with amblyopia, aged 5-17 years. The main question it aims to answer is: Is a 16-week course of amblyopia treatment using Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for approx. 25 min/day, 6 days/week more effective for improvement in amblyopic-eye VA, binocularity (stereoacuity, suppression, alignment), contrast sensitivity, attention, oculomotor function, visual-motor integration, and quality of life than 16 weeks of continued glasses alone? Participants will each serve as their own control and complete: Treatment period 1: Continued optical correction (glasses) alone for 16 weeks; Treatment period 2: Vivid Vision Therapeutic (Dichoptic) Virtual Reality Games for 16 weeks (approx. 25min/day, 6 days/week) plus continued optical correction

NCT ID: NCT05957458 Completed - Myopia Clinical Trials

Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults

MCPT
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of exposure to induce the myopia control effect. The efficacy of the low-level red-light technology has been proven in a Chinese populationb for the recent 3 years with evidence based papers and amazing results. However, there's not yet evidence to demonstrate the relationship between the dose response effect of photobiomodulation therapy on myopia control at the different age lever.

NCT ID: NCT05811598 Recruiting - Myopia Clinical Trials

Real Word Study on Myopia Control With Repeated Red Light Therapy for Ages of 3~6 Years Old

RMC
Start date: March 21, 2023
Phase: N/A
Study type: Interventional

Repeated Red Light Therapy had been used as an amblyopia therapy for children as well as the myopia control in primary schools. However, ultra low lever of red light therapy with irradiance of 0.37mW and 0.60mW effectiveness and safety for 3~ 6 year-old myopia treatment or slow myopia progression are seldom reported.

NCT ID: NCT05732467 Recruiting - Amblyopia Clinical Trials

Effectiveness of Virtual Reality Training in Amblyopia

Start date: November 14, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the efficacy and safety of visual function training software (model: SJ-JRS2021) in the treatment of mild to moderate amblyopia in children. The main questions it aims to answer are: - Whether virtual reality training is more effective than occlusion therapy - Safety of virtual reality training in amblyopia treatment If participants have refractive problems, correct the refraction first and wear corrective glasses. The experimental group will be treated using visual function training therapy software (model: SJ-JRS2021). The control group will be treated with occlusion therapy covering the contralateral eye for 2 hours a day. Researchers will compare experimental group with control group to see if the experimental group has better corrected vision recovery.

NCT ID: NCT05714449 Recruiting - Amblyopia Clinical Trials

OCT Eccentric Fixation and Amblyopia in Children

Start date: January 25, 2023
Phase: N/A
Study type: Interventional

The objectives of this proposal are to characterize the relationship between OCT eccentric fixation (OCT-EF), fixation eye movement (FEM), macular sensitivity in children with amblyopia.

NCT ID: NCT05705778 Recruiting - Amblyopia Clinical Trials

Plasma Biomarker in Amblyopia Patients

Start date: November 1, 2022
Phase:
Study type: Observational

This prospective study aims to observe the predictive effect of peripheral blood plasma biomarker on the outcome of treatment in children with different types of amblyopia. We also investigated the mechanism of neuromodulation in the visual development of amblyopic children.

NCT ID: NCT05620173 Recruiting - Amblyopia Clinical Trials

Validation of New Virtual Reality Treatment for Children With Lazy Eye Using the Vedea Amblyopia Therapy (VAT)

VAT
Start date: February 22, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to validate the effectiveness of the Vedea Amblyopia Therapy (VAT) as a treatment for children with lazy eye. The main question it aims to answer is to prove that the VAT is as effective or more effective than the current gold standard for treating children with lazy eye. This is occlusion therapy by patching the dominant eye. Participants will play VR-games specifically designed for children with lazy eye for 30 minutes per day, 5 days per week for 16 weeks. This group of children will be compared to children that undergo regular occlusion therapy to see how both treatments options compare.

NCT ID: NCT05612568 Active, not recruiting - Amblyopia Clinical Trials

5 Years of Eye Screening for ARF in Children Aged <3 Years in Flanders

Start date: September 1, 2022
Phase:
Study type: Observational

In this research we will investigate the distribution and evolution of amblyopia risk factors and other refractive errors in children younger than 3 years of age. The significance and magnitude of current global evolutions in ARF and refractive errors will be verified to update current guidelines and practices. Better insight in associated factors of amblyopia risk factors will contribute to current understanding of amblyopia.

NCT ID: NCT05588362 Not yet recruiting - Myopia Clinical Trials

Access to EyeGlasses for School-aged Children

ATEG
Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Uncorrected refractive error is a leading cause of visual impairment in children and can impact vision, quality of life, and academic performance. Despite Boston Children's Hospital serving patients from a wide range of socioeconomic backgrounds, there are health disparities in access to eyeglasses as a consequence of patients' health insurance. The investigators will examine whether the use of an in-clinic app for 3-D printed glasses reduces disparities in access to eyeglasses for our patients on Medicaid. The intervention will address social determinants of health and improve pediatric health outcomes namely, how and when children having publicly funded health insurance receive eyeglasses. The short-term objectives are (1) to compare the time to receive glasses between publicly funded MassHealth eyeglasses and an in-clinic order of 3D printed glasses (2) to evaluate compliance with glasses wear in these two groups, and (3) to evaluate visual function and quality-of-life outcomes in these two groups. This prospective randomized control study will evaluate barriers to accessing eyeglasses in school-aged children. The investigators will recruit children enrolled in MassHealth and randomize them into two cohorts: (1) the control group will receive MassHealth glasses as per standard of care, through an optical shop of their choosing, or (2) the intervention group will use an app for immediately ordering glasses (paid for by the study) in clinic following their appointment. The investigators will evaluate the time needed to receive eyeglasses, compliance with glasses wear, quality of life, and visual outcomes between the cohorts at one-, three-, and six-month intervals. Through this project, the investigators will not only evaluate, quantify, and bring awareness to disparities in our patient population, but will also look toward finding a solution through the use of a novel application that addresses many of the barriers faced by patients insured through Medicaid.

NCT ID: NCT05522972 Recruiting - Amblyopia Clinical Trials

Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games

Start date: September 13, 2022
Phase: N/A
Study type: Interventional

Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. This study uses psychophysical measures to study neural plasticity in both adults and children with amblyopia.