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Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care — MADCO-PC  

Postoperative Delirium Clinical Trial

Official title:
Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care

Clinical Trial Summary

This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal cord (i.e. cerebrospinal fluid, or CSF), and/or changes in brain connectivity. The investigators will also examine whether different types of anesthesia have different effects on these CSF markers of Alzheimers disease, or different effects on thinking and memory after anesthesia and surgery, or differential effects on the correlation between cognitive changes and CSF marker changes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01993836
Study type Interventional
Source Duke University
Contact
Status Completed
Phase Phase 4
Start date November 2013
Completion date January 10, 2019
View Details
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