Amyloid-beta PET Imaging With 18F-92 in Alzheimer's Disease

Status Recruiting

Clinical Trial Summary

Alzheimer's disease is a neurodegenerative disease. Numerous studies have reported that β-amyloid (Aβ) is an important marker for the diagnosis of AD. 18F-92 molecular probe is a novel molecularly targeted imaging agent, which can rapidly penetrate the blood-brain barrier and has high affinity and selectivity for Aβ protein. In this study, 18F-92 PET/CT was used to monitor the regional distribution and the degree of deposition in patients with Alzheimer's disease, and compared with clinical symptoms (neuropsychometry) to evaluate its application value in the diagnosis of AD.

Clinical Trial Description

Healthy volunteers as well as patients meeting Alzheimer's criteria will be recruited for this study. We will use PET/CT imaging technology to scan each participant's whole body or head and collect image data for analysis to evaluate the distribution and metabolism of 18F-92 in the subject's body. Time from drug injection to scan completion is approximately 1 hour. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04926272
Study type	Interventional
Source	First Affiliated Hospital of Fujian Medical University
Contact	Shaobo Yao, PhD
Phone	86-0591-87981618
Email	yaoshaobo008@163.com
Status	Recruiting
Phase	Phase 2
Start date	July 1, 2021
Completion date	July 1, 2024

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