Alzheimer's Disease Clinical Trial
Official title:
Study of the Predictive Markers and the Pathophysiological Mechanisms of Alzheimer's Disease: Transverse and Longitudinal Approach in Anatomical and Functional Multimodal Imaging
According to estimations, Alzheimer's disease affects approximately 860,000 people aged of
more than 65 years in France. This disease is characterized by disorders of cognitive
functions, including memory, associated with structural and functional modifications of the
brain. These changes are evolving within the pathology progression and can be evaluated with
neuropsychological tests (to assess capabilities such as language, orientation, etc.) and
also with brain imaging (e.g. MRI). Alzheimer's disease is still poorly understood,
nevertheless currently available treatments can slow its development if the disease is
diagnosed early enough.
Thus, the objective is to identify markers for early diagnosis of Alzheimer's disease, to
better describe the evolution of this disease.
The three main objectives of this project are
- to identify, compare and combine predictive markers of Alzheimer's disease
- to make a significant contribution to the understanding of the pathophysiological
mechanisms of Alzheimer's disease
- to study the ability of different neuroimaging techniques to follow the evolution of
this pathology.
n/a
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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