Alzheimer's Disease Clinical Trial
Official title:
A Randomised Placebo Controlled Trial of a Cholinesterase Inhibitor in the Management of Agitation in Dementia That is Unresponsive to a Psychological Intervention
Primary Aim
To determine whether;
- Donepezil is significantly better than placebo in the management of agitation in
Alzheimer's Disease that has not responded to, or is inappropriate for a standardised
brief psychosocial treatment
Secondary Aims
To determine whether;
- Donepezil has a significant positive or negative impact upon quality of life compared
with placebo
- whether there is a significant difference between Donepezil and placebo with respect to
cognitive performance
- the cost effectiveness of the pharmacological treatment for agitation
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Prevention
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