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Clinical Trial Summary

This study aims to validate the safety and impact of transdermal trigeminal electrical neuromodulation(Cefaly) on mild cognitive impairment patients with insomnia on brain functional and structural connectivity as well as sleep parameters evidenced by polysomnography and sleep surveys, with consideration for amyloid positivity and brain-derived neurotrophic factor .


Clinical Trial Description

This study aims to validate the safety and impact of transdermal trigeminal electrical neuromodulation(Cefaly) on mild cognitive impairment patients with insomnia on brain functional and structural connectivity as well as sleep parameters evidenced by polysomnography and sleep surveys, with consideration for amyloid positivity and brain-derived neurotrophic factor . A 3-month intervention with transdermal trigeminal electrical neuromodulation will be implemented and sleep surveys, polysomnography and brain MRI will be attained both at baseline and post-intervention. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05200897
Study type Interventional
Source Saint Vincent's Hospital, Korea
Contact Yoo Hyun Um
Phone +821063759332
Email [email protected]
Status Recruiting
Phase N/A
Start date November 3, 2021
Completion date May 31, 2023

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