Virtual Environment to Aid Cognitive Stimulation of Elderly People With Early Alzheimer's

Alzheimer Disease Clinical Trial

Official title:

Virtual Environment to Aid Cognitive Stimulation of Elderly People With Early Alzheimer's

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04919005
• Other study ID #: CAAE: 54290416.9.0000.5497
• Status: Completed
• Phase: N/A
• Start date: July 1, 2016
• Est. completion date: July 20, 2017

Study information

• Verified date: June 2021
• Source: University of Mogi das Cruzes
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This research was carried out with the objective of verifying the possibility of intervention through cognitive training protocols to assist in the stimulation of neurons and to delay the degradation resulting from Alzheimer's disease in its initial phase. The specific objective of this research was to develop and validate a virtual environment of games (called SorrisoTur) that allows the intervention of cognitive training.

Description:

SorrisoTur encompasses cognitive training concepts and protocols in playful situations, which were coded in the form of 2D mini-games that are run on a computer connected to the Web, and designed to stimulate cognitive domains, such as memory, executive functions, spatial-visual skills, language (expression, comprehension, reading, and writing) and personality/behavior. For the comparison of results, three groups were created; one group of elderly people with Alzheimer's disease at an early stage, one group formed by healthy elderly, and another group with young people and applied Mini-Mental State Examination (MMSE) and Wechsler Intelligence Scale for Adults (WAIS-III) before and after of interventions with the games.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 34
• Est. completion date: July 20, 2017
• Est. primary completion date: April 30, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 19 Years to 99 Years

Eligibility

Inclusion Criteria:

• People with physical or psychological conditions allow interacting with digital games;
• Elderly over 60 years with mild Alzheimer;
• Seniors over 60 Healthy;
• Healthy Youth;

Exclusion Criteria:

• People without physical or psychological conditions allow interacting with digital games;
• Elderly people over 60 years old who have any type of dementia other than Alzheimer, or moderate or severe Alzheimer;

Related Conditions & MeSH terms

• Alzheimer Disease

Intervention

Other:
• Virtual Environment
The Virtual Environment was called SorrisoTur and consists of 10 mini-games with difficulty levels in a limited number of cities and mini-games distributed in a thematic scenario of the map of Brazil. The virtual environment consists of the cognitive training mini-games within a theme for all screens, mini-games, and information. The interventions with the Virtual Environment were administered in periods of one hour, twice a week, for a month.

Locations

Country	Name	City	State
Brazil	Terigi Augusto Scardovelli	Mogi das Cruzes	São Paulo

Sponsors (1)

Lead Sponsor	Collaborator
University of Mogi das Cruzes

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change on Wechsler Intelligence Scale for Adults (WAIS-III)	The WAIS-III is an intellectual assessment that aims to analise the measures of the following Factorial Scales and Indexes: Verbal IQ (intelligence quotient), Execution IQ, Total IQ, Verbal Understanding Index, Perceptual Organization Indexes, Operational Memory Indexes and Processing speed index.	Baseline and after 4 weeks
Primary	Change on Mini Mental State Examination (MMSE)	The MMSE is a data collection instrument widely used in cases of dementia, it evaluates temporal and spatial orientation, short-term memory (immediate or attention) and skills of evocation, calculation, praxis, visuospatial, communication and language.	Baseline and after 4 weeks