Alzheimer Disease Clinical Trial
— TGenOfficial title:
Early Onset Alzheimer's Disease Genomic Study
NCT number | NCT03645993 |
Other study ID # | 017-176 |
Secondary ID | |
Status | Recruiting |
Phase | |
First received | |
Last updated | |
Start date | June 16, 2017 |
Est. completion date | June 16, 2022 |
The purpose of this study is to collect samples from patients with Early-Onset Alzheimer's disease (AD) and their immediate family members for molecular analysis. Samples will be studied in order to understand how molecular changes in the body are related to the development of the disease. Researchers will study your DNA and RNA in order to help doctors diagnose, treat, and monitor people at risk of developing Early-Onset AD in the future.
Status | Recruiting |
Enrollment | 2 |
Est. completion date | June 16, 2022 |
Est. primary completion date | June 16, 2022 |
Accepts healthy volunteers | |
Gender | All |
Age group | 40 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Diagnosis of early-onset Alzheimer's disease based on the NIA-AA diagnostic criteria as determined by the clinician. (Those patients with severe dementia due to Alzheimer's disease or who have impaired decisional capacity, may participate only if their legally authorized representative gives their consent.) - Male and female patients =40 and =65 years of age. - Parents and siblings of the participant with Alzheimer's disease. Exclusion Criteria: - Family history of early or late-onset Alzheimer's disease. - Uncontrolled concurrent illness including psychiatric illness or situations that would limit compliance with the study requirements or the ability to willingly give written or verbal informed consent |
Country | Name | City | State |
---|---|---|---|
United States | Baylor Scott & White AT&T Memory Center | Dallas | Texas |
Lead Sponsor | Collaborator |
---|---|
Baylor Research Institute | Translational Genomics Research Institute |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Biomarkers found in blood | Blood will be taken so that tests can be run to locate a biomarker that will help to diagnose and treat early-onset Alzheimer's disease. | 2 years |
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