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Clinical Trial Summary

A single-center, open-label baseline controlled imaging study designed to assess whether brain tau fibril uptake of flortaucipir as measured by PET correlates with cognitive status of individuals with and without brain tau fibrils.


Clinical Trial Description

This project will collect quantitative pilot data that will allow the characterization of uptake and binding of 18F-AV-1451 (also known as F 18 T807), a novel tau imaging compound, in individuals with and without brain tau fibrils. The primary goal is to develop tau imaging technique as an antecedent biomarker of cognitive decline. The investigators propose to obtain preliminary data that will support the possibility of detecting cognitive decline in its earliest stages, before the occurrence of dementia. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02414347
Study type Observational
Source Washington University School of Medicine
Contact Kelley M Jackson, BA
Phone 314 362-1558
Email kelleyj@wustl.edu
Status Recruiting
Phase
Start date October 23, 2014
Completion date December 2024

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