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A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

Sarcoma Clinical Trial

Official title:
A Phase II Study of Concurrent Systemic Pembrolizumab and Isolated Limb Infusion (ILI) With Melphalan and Dactinomycin for Patients With Locally Advanced or Metastatic Extremity Sarcoma

Clinical Trial Summary

The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm or leg using a technique called isolated limb infusion (ILI), is a safe treatment that can delay the time before your disease gets worse (progresses).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04332874
Study type Interventional
Source Memorial Sloan Kettering Cancer Center
Contact Edmund Bartlett, MD
Phone 212-639-2448
Email bartlete@mskcc.org
Status Recruiting
Phase Phase 2
Start date April 1, 2020
Completion date April 1, 2025
View Details
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