Alveolar Bone Loss Clinical Trial
Official title:
Using Boned-Apatite Cement at the Time of Extractions for Ridge Preservation at These Sites
To assess efficiency of ridge preservation (in vertical and horizontal dimensions) after tooth extraction using Calcium Sulfate with hydroxyapatite(®Bond-apatite) compared to the use of bovine bone substitute (BioOss®) and to extration only as negative control.
Dental implants have become in the past ten years a popular and promising treatment in the
rehabilitation of missing teeth. However, using implants depends on adequate alveolar bone
volume. Anatomical restrictions are mostly present in posterior mandibular and maxillary
regions. Alveolar bone loss usually occurs because of active periodontal disease, trauma or
teeth extractions.
Teeth extractions are associated with some loss of alveolar bone in the horizontal and
vertical dimensions. This loss is more pronounced when teeth are extracted because of
periodontal disease. Bone grafts from different origins (autogenic, allogenic, xenogenic or
alloplastic) can partly reduce the alveolar bone loss. Different ridge preservation
techniques were succesfully used in clinical trials, using membranes only or as a combination
of membranes and bone substitutes.
Synthetic bone grafts have been proven successfully for ridge preservation. Calcium sulfate
is the oldest material, being in use in dentistry for more than 30 years , and in orthopedics
for more than 100 years . Calcium sulfate is completely absorbed and constitutes a matrix on
wich bone is able to grow (osteoconductive). It does not induce inflammation and doesn't
alter calcium levels in the blood flow.Previous studies has shown that calcium sulfate is
completely replaced by bone. On the other hand, fast absorption of calcium sulfates can alter
the dimensional stability of the graft. Adding Hydroxy Appatite may improve stability during
bone remodeling.
This study includes patients who need extractions of incisors, canines or premolars. The
extraction sockets must be mostly intact with a maximum 4 mm of one wall missing in the
vertical dimension.
30 patients who need extractions from region of interest, with no extended bony defects, will
be enrolled from the department of Periodontology, school of graduate dentistry, Rambam
Health Care Campus
;
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