Alveolar Bone Atrophy Clinical Trial
Official title:
Dimensional Changes of the Alveolar Ridge Contour After Socket Preservation, Stability of Implants Placed, and Histological Evaluation of Newly Formed Bone at These Sites.
In this study, the investigators will evaluate the dimensional changes of alveolar bone in
the preserved sites in comparison with extraction only conventional healed sockets, as well.
1. Dimensional changes of the alveolar ridge contour after socket preservation in
comparison to conventional tooth extraction.
2. Evaluation the stability of implants placed at the preserved sockets.
3. Histological evaluation of newly formed bone at the socket preserved sites in
comparison with extracted only healed sites.
Nineteen systematically healthy patients (10 female and 9 male; mean age 38 years old; range
19-57) providing 32 hopeless non-molar teeth were selected and divided into 2 treatment
groups: In the test group, following tooth extraction, for 16 sockets (9sockets from 5
female and 7 sockets from 5 male patients) soft and hard tissue measurements include
horizontal (Bucco-Lingual dimensions at 1mm,3mm and 7mm at the mid portion from the line
connecting two adjacent CEJs) and vertical ridge dimensions (vertical distance from the line
connecting two adjacent CEJs at 8 points: Mid-Buccal, Mid-Lingual, Mesial, Distal,
Disto-Buccal, Disto-Lingual, Mesio-Buccal, Mesio-Lingual around the socket) will be
determined using a caliper and a template. All sockets will be filled with DFDBA and covered
with absorbable membrane. Primary coverage will be achieved by full thickness mucosal flap
advancement over each socket. Then an acid-etch bridge will be applied for the sites, both
to avoid the movement of adjacent teeth to the empty space & also for patients esthetics. 6
months following the procedure, the soft and hard tissue in all the sites will be measured
again as it was mentioned previously, plus the measurements gained from CBCT radiographs.
Besides, biopsy will be harvested from some of the preserved sites that has enough width
with the use of trephine bur no.3 and it was sent for histological evaluation. Subsequently,
Implants will be installed in the preserved sites and the implant stability will be measured
with the help of Ostell device. The stability will be measured after 4 month following
implant insertion with the same device while the implant undergoes the implant exposure
procedure.
In control group, 16 sockets (9 sockets from 5 female, and 7 sockets from 4 male patients)
served as unfilled extraction only group. Following extraction, soft and hard tissue
measurements (horizontal and vertical ridge dimensions) will be determined with the use of
caliper and template.
6month after extraction, CBCT will be taken from the site and at the time of implant
installation, the soft and hard tissue in all sites will be measured in vertical and
horizontal dimensions. Furthermore, biopsy from some of the healed sockets with enough width
will be taken with the use of trephine bur no.3 and it will be sent for histological
examination.
;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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