Evaluation of Some Prognostic Factors in Acute Aluminum Phosphide Intoxicated Cases

Aluminum Phosphide Poisoning Clinical Trial

Official title:

Evaluation of Some Prognostic Factors in Acute Aluminum Phosphide Intoxicated Cases

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05215444
• Other study ID #: 6665
• Status: Completed
• Start date: January 1, 2021
• Est. completion date: June 30, 2021

Study information

• Verified date: January 2023
• Source: Zagazig University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

study of some laboratory and clinical findings which may show the severity of aluminium phosphide toxicity and the need of the cases to be admitted to ICU

Description:

aluminium phosphide poisoning is a major cause of death in intoxicated and suicidal cases since there is no antidote and there is no specific investigation for it so there is a need for further study to identify the cause of death and the most specific investigation in the case of AlP toxicity

Recruitment information / eligibility

• Status: Completed
• Enrollment: 42
• Est. completion date: June 30, 2021
• Est. primary completion date: January 30, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 15 Years to 45 Years

Eligibility

Inclusion Criteria:

1. History of exposure or intake of Aluminum phosphide.

2. Clinical picture of Acute Aluminum phosphide poisoning including severe vomiting, hypotension, abdominal pain, cardio-pulmonary distress.

3. Cases of the age of 15 to 45 years old

Exclusion Criteria:

• 1. Cases with an unclear history. 2. History of co-morbidities or systemic diseases because of the possibility of misleading laboratory results.

3. History of co-ingestion of drugs or another poison.

Related Conditions & MeSH terms

• Aluminum Phosphide Poisoning
• Poisoning

Intervention

Diagnostic Test:
• some prognostic factors
cortisol level, renin, troponin I, MDA ,catalase, super oxide dismutase, liver functions, kidney functions, arterial blood gases, sodium level, potassium level. white blood cells count

Locations

Country	Name	City	State
Egypt	Faculty of Medicine Zagazig University	Zagazig	Sharkia

Sponsors (1)

Lead Sponsor	Collaborator
Zagazig University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	prognosis	predict the mortality of intoxicated AlP cases	the first 24 post poisoning