Effect of Isocaloric Ketogenic Diet on Physical Performance at High Altitude — ICKD  

Physical Activity Clinical Trial

Official title: Effect of a Four-week Isocaloric Ketogenic Diet on Physical Performance at Very High Altitude: a Pilot Study

Status Completed

Clinical Trial Summary

A ketogenic diet (KD) reduces daily carbohydrates (CHOs) ingestion by replacing most calories with fat. KD is of increasing interest among athletes because it may increase their maximal oxygen uptake (VO2max), the principal performance limitation at high altitudes. The investigators examined the tolerance of a 4-week isocaloric KD (ICKD) under simulated hypoxia and the possibility of evaluating ICKD performance benefits with a maximal graded exercise bike test under hypoxia and collected data on the effect of the diet on performance markers and arterial blood gases.

Clinical Trial Description

In a randomised single-blind cross-over model, 6 recreational mountaineers (age 24 to 44 years) will complete a 4-week ICKD followed or preceded by a 4-week habitual mixed western diet (HD). Performance parameters (VO2max, lactate threshold [LT], peak power [Ppeak]) and arterial blood gases (PaO2, PaCO2, pH, HCO3-) will be measured at baseline under two conditions (normoxia and hypoxia) as well as after a 4-week HD and 4-week ICKD under the hypoxic condition. ;

Related Conditions & MeSH terms

• Altitude Hypoxia
• Altitude Sickness
• Hypoxia
• Ketogenic Dieting
• Physical Activity

• NCT number: NCT05603689
• Study type: Interventional
• Source: Clinique Romande de Readaptation
• Status: Completed
• Phase: N/A
• Start date: September 1, 2020
• Completion date: September 23, 2022