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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT06370442
Other study ID # 2137695
Secondary ID
Status Not yet recruiting
Phase Phase 3
First received
Last updated
Start date June 1, 2024
Est. completion date September 1, 2025

Study information

Verified date April 2024
Source State University of New York - Upstate Medical University
Contact Jay M Brenner, MD
Phone 315-464-1861
Email brennerj@upstate.edu
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of the study is to determine if intranasal dexmedetomidine could be an alternative to the current standard of care (injectable benzodiazepines or antipsychotics) for sedation prior to computerized tomography (CT) or magnetic resonance imaging (MRI) in those greater than or equal to 65 years of age (older adults) that are seen in the Emergency Department (ED).


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Study Design


Related Conditions & MeSH terms


Intervention

Drug:
Dexmedetomidine
Intranasal dexmedetomidine, 100mcg
Lorazepam
0.5mg IV
Haloperidol
0.5mg IV

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
State University of New York - Upstate Medical University

References & Publications (11)

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Outcome

Type Measure Description Time frame Safety issue
Primary Sedation The primary outcome is to determine if intranasal dexmedetomidine is as effective in producing moderate sedation on the Modified Observer's Assessment of Alertness/Sedation Scale (MOAAS) as standard of care intravenous medications in older adults. The minimum value on the Modified Observer's Assessment of Alertness/Sedation Scale is 0 and the maximum value is 5. Lower scores mean a worse outcome. Within one hour of administration
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