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Alopecia Totalis/Universalis clinical trials

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NCT ID: NCT01314495 Withdrawn - Clinical trials for Alopecia Totalis/Universalis

Abatacept Costimulatory Blockade in the Treatment of Alopecia Totalis/Universalis

Start date: September 2011
Phase: Phase 2
Study type: Interventional

Will Abatacept reduce priming of the hair follicle specific T cells and thereby reduce hair follicle associated infiltration and improve hair growth. This is a double blind placebo controlled study to test the safety and efficacy of Abatacept in the treatment of 64 subjects diagnosed with alopecia totalis or alopecia universalis. Subjects will be randomized 1:1 to the placebo or treatment arm and will receive 6 months of treatment with the study medication or placebo, followed by a 6 month observational period.