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Randomized, Double-Blind, Placebo-Controlled Phase 2a, Proof-of-Concept Trial of ADX-914 Phase 2a Trial for the Treatment of Severe Alopecia Areata — SIGNAL-AA  

Alopecia Areata Clinical Trial

Official title:
A Phase 2a, Randomized, Double-blind, Placebo-Controlled, Proof-of-Concept Trial of ADX-914 for the Treatment of Severe Alopecia Areata

Clinical Trial Summary

This is a Phase IIa, Randomized, Double-blind, Placebo-controlled, multi-center Proof-of-Concept (POC) Trial in subjects with severe Alopecia Areata.

Clinical Trial Description

This is a Phase IIa, Randomized, Double-blind, Placebo-controlled, multi-center Proof-of-Concept (POC) study in adult subjects with severe Alopecia Areata (AA). ADX-914 or matching placebo is administered subcutaneously in the clinic setting every 2 weeks for 24 weeks, with follow-up for 12 weeks. Subjects will be randomized 3:1 to drug vs placebo. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06018428
Study type Interventional
Source Q32 Bio Inc.
Contact
Status Active, not recruiting
Phase Phase 2
Start date August 28, 2023
Completion date December 2024
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