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Clinical Trial Summary

This is a prospective, randomized, double blind, placebo-controlled clinical trial. The study will take place at 4 sites. This trial will enroll a total of 68 patients with moderate to severe AA (affecting more than 50% of the scalp) at the time of screening with a targeted 54 subjects completers through Week 48. AA subjects must have evidence of hair regrowth within the last 7 years of their last episode of hair loss; and have screening IgE ≥ 200 and/or have personal and/or familial history of atopy. Subjects will be randomized (2:1) to either receive weekly dupilumab or placebo for 48 weeks, with all subjects completing participation through Week 48 receiving an additional 48 weeks of dupilumab (through Week 96).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05551793
Study type Interventional
Source Icahn School of Medicine at Mount Sinai
Contact Giselle Singer
Phone 212-241-3288
Email giselle.singer@mssm.edu
Status Recruiting
Phase Phase 2
Start date April 10, 2023
Completion date December 2025

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