Regeneron AA Multicenter (Dupilumab)

Status Recruiting

Clinical Trial Summary

This is a prospective, randomized, double blind, placebo-controlled clinical trial. The study will take place at 4 sites. This trial will enroll a total of 68 patients with moderate to severe AA (affecting more than 50% of the scalp) at the time of screening with a targeted 54 subjects completers through Week 48. AA subjects must have evidence of hair regrowth within the last 7 years of their last episode of hair loss; and have screening IgE ≥ 200 and/or have personal and/or familial history of atopy. Subjects will be randomized (2:1) to either receive weekly dupilumab or placebo for 48 weeks, with all subjects completing participation through Week 48 receiving an additional 48 weeks of dupilumab (through Week 96).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05551793
Study type	Interventional
Source	Icahn School of Medicine at Mount Sinai
Contact	Giselle Singer
Phone	212-241-3288
Email	giselle.singer@mssm.edu
Status	Recruiting
Phase	Phase 2
Start date	April 10, 2023
Completion date	December 2025

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See also
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