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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT04964349
Other study ID # Alazhar faculty of medicine
Secondary ID Ahmed KadahEman
Status Recruiting
Phase Early Phase 1
First received
Last updated
Start date April 21, 2021
Est. completion date November 20, 2021

Study information

Verified date July 2021
Source Al-Azhar University
Contact Ahmed pr Elshahid, MD
Phone 00201006262271
Email ahmedandro@yahoo.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Alopecia areata is believed to be an autoimmune disease. Treatment primarily relies on intralesional and topical corticosteroids. This study was conducted to evaluate Jessener Solutionas a potential therapeutic modality of Alopecia Areataversusintralesional steroid as regards the efficacy, safety, tolerability, and patients' satisfaction.


Description:

Background Alopecia areata is believed to be an autoimmune disease resulting from a breach in the immune privilege of the hair follicles causing non scarring hair loss.Treatment primarily relies on intralesional and topical corticosteroids.Up till now, there is nouniversally proven therapy that induces and maintains remission of Alopecia Areata in all patients. Aims The Aim of Study is to evaluate the efficacyof Jessener solution versus intralesional steroid in treatment of Alopecia Areata. Patients and Methods The study will include 40 patients diagnosed clinically and dermoscopically as Alopecia Areata with more than two patches of alopecia areata were included. Two treatment modalities with intralesional corticosteroid and topical Jessener Solutionas were performed in two randomly selected patches. Three sessions were done, 3 weeks apart and were followed-up for three months. Evaluation was done using Mac Donald Hull and Norris grading system , Serial photographs and dermoscopic , trichoscopic examination every month will be done and patient will be score.


Recruitment information / eligibility

Status Recruiting
Enrollment 40
Est. completion date November 20, 2021
Est. primary completion date October 21, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 12 Years to 40 Years
Eligibility Inclusion Criteria: - 1.Alopecia Areatamultilocuolaris.2.Age from18-50years old. 3.Wash out period is two months. 4.Ophiasis pattern alopecia areata. Exclusion Criteria: - Age less than 12 yearsand more than 40years old. 2.Patient under treatment.3.Patients having another dermatological condition affecting thescalpas eczema.4.Patients with psychiatric disorders.5.Pregnant and lactating females.

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
Corticosteroids Acting Locally
topical application of jessener solution

Locations

Country Name City State
Egypt Alazhar faculty of meidicine Cairo

Sponsors (1)

Lead Sponsor Collaborator
Al-Azhar University

Country where clinical trial is conducted

Egypt, 

Outcome

Type Measure Description Time frame Safety issue
Primary Effecacy of topical jessener solution in treatment of alopecia areata Effecacy of topical jessener solution in treatment of alopecia areata 6 monthes
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