A Study of Vitamin D in Subjects With Alopecia Areata

Alopecia Areata Clinical Trial

Official title:

A Pilot Study of Vitamin D in Subjects With Alopecia Areata

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01328678
• Other study ID #: ARI-1270-Alopecia
• Status: Completed
• Phase: N/A
• First received: January 6, 2011
• Last updated: July 6, 2011
• Start date: August 2009
• Est. completion date: July 2011

Study information

• Verified date: July 2011
• Source: Avera McKennan Hospital & University Health Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The objective of this study is to assess the parathyroid-vitamin D-calcium axis in subjects with alopecia areata. The hypothesis behind this study is that hypovitaminosis D might contribute to the pathogenesis of alopecia areata.

Description:

Alopecia Areata (AA) is a T-Cell mediated, non-scarring, polygenic, autoimmune disease of the hair follicle. It has been reported to be associated with other autoimmune diseases, especially autoimmune thyroid disease and vitiligo. It is more common in females. Recently, vitamin D deficiency has been claimed to contribute to the pathogenesis of multiple autoimmune disease. There is a strong inverse correlation between the level of 25-hydroxyvitamin D levels and the autoimmune disease in adolescents.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: July 2011
• Est. primary completion date: July 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Men and women who are at least 18 years old

• Subjects with newly diagnosed with alopecia areata

Exclusion Criteria:

• Subjects who take supplemental Vitamin D, by itself or as a part of a multivitamin

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Alopecia
• Alopecia Areata

Locations

Country	Name	City	State
United States	Avera Research Institute	Sioux Falls	South Dakota

Sponsors (1)

Lead Sponsor	Collaborator
Avera McKennan Hospital & University Health Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Vitamin D levels will be reported in subjects and correlated with the calcium and parathyroid levels.	This study consists of a single clinic visit. After subject has completed the informed consent process and meets eligibility criteria, a blood sample will be collected. Lab results from this one-time lab draw will be evaluated.	Initial clinic visit (day 1)	No