Study for the Prediction of Active Rejection in Organs Using Donor-derived

Status Recruiting

Clinical Trial Summary

Clinical Trial Description

This is a multi-center prospective study designed to collect blood samples from transplant patients in order to improve Natera's method for determining allograft rejection status using the donor-derived cell-free DNA analysis, called Prospera. Subjects who have had an organ transplant, who present at the clinic for a standard of care visit or consent for an extra research blood samples to be taken by mobile phlebotomy, meet the study's eligibility criteria and are willing to participate in this research, will be consented and enrolled in this study. Subjects will provide at least one blood sample at study enrollment and up to three optional follow-up blood samples at future visits. Relevant medical data will also be collected for each patient enrolled. Urine samples may also be collected at the above described time-points. Up to 500 subjects over the age of 2 worldwide who meet the study eligibility criteria are expected to be enrolled in this study. The study includes adult, pregnant, and pediatric subjects. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03984747
Study type	Observational
Source	Natera, Inc.
Contact	Zach Demko, PhD
Phone	6502499090
Email	zdemko@natera.com
Status	Recruiting
Phase
Start date	September 14, 2018
Completion date	October 30, 2028

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Study for the Prediction of Active Rejection in Organs Using Donor-derived Cell-free DNA Detection — SPARO

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms