Allogeneic Disease Clinical Trial
Official title:
A Pilot Study of the Feasibility of Setting up a Logbook for Allogeneic Haematopoietic Stem Cell Patients at the University Hospital of Amiens
Hospitalization for allogeneic haematopoietic stem cell transplantation constitutes a
particular time in the management of patients with malignant hemopathies both for the
patient, for his entourage or for the nursing staff. For the patient, the strict protective
isolation set up during this period is a source of isolation in the broad sense and is
associated with an escape from external events and society. It also constitutes a physical
barrier (mask, charlotte, surblouse and overshoes worn by caregivers or visitors) and even
psychological in relations with relatives. Moreover, this period is also difficult because of
the possible complications of conditioning (mucositis, transit disorders, fever ...) and
allograft itself (graft versus host disease, no transplant, relapse disease…). The patient
may be weakened and diminished, which can give a feeling of helplessness and uselessness to
the family. Finally, this therapy can have serious physical and psychological consequences
for the patient and his entourage (especially in the case of family allograft) who do not
always have the possibility to express themselves verbally. Published studies in hematology
report depressive, anxious and post-traumatic stress disorders in patients and relatives
during allogeneic haematopoietic stem cell transplantation. It is therefore important to
reduce these symptoms, particularly those related to the cut-off during hospitalization for
allogeneic haematopoietic stem cells.
Over the last decade or so, the logbook has been used in some resuscitation services in
intubated patients, with the main objective of filling the "memory gap" mentioned by the
intubated patients when they woke up and limiting the trauma associated with this Cut in the
world corresponding to the sedation period. For this purpose, the use of a logbook in
Hematology, by analogy with what is used in the resuscitation services, could be a means of
limiting the psychological complications related to the allograft.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04966156 -
Cancer Rehab Program for Allogenic Bone and Marrow Transplant Patients - CaRE-4-alloBMT
|
N/A | |
| Not yet recruiting |
NCT05855707 -
Wharton Jelly Mesenchymal Stromal Cells as GVHD Prophylaxis
|
Phase 1 | |
| Recruiting |
NCT05579678 -
APOLLO: Personalized rehAbilitation PrOgram in aLLOgeneic Bone Marrow Transplantation
|
||
| Completed |
NCT03343834 -
Methyl-qPCR : a New Predictive Marker for Epstein-Barr Virus-associated Lymphoproliferations During Allogeneic Hematopoietic Stem Cell Transplantation
|
N/A | |
| Active, not recruiting |
NCT03371667 -
To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids
|
Phase 3 |