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NCT03182491 Clinical Trial

Mechanisms of Anaphylaxis

Allergy Clinical Trial

— ANAMEK  

Official title:
Mechanisms of Anaphylaxis

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT03182491
Other study ID # 2016/1635
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date April 28, 2017
Est. completion date October 1, 2026

Study information
Verified date August 2022
Source Haukeland University Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

The purpose of this study is to explore different mechanisms for anaphylaxis and find novel biomarkers for this hypersensitivity syndrome. The study participants are patients with anaphylaxis, patients with mild allergic reactions, and patients with febrile transfusion reactions. The investigators will also include a group of healthy controls.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 40
Est. completion date October 1, 2026
Est. primary completion date October 1, 2026
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 16 Years to 120 Years
Eligibility Inclusion Criteria: According to the specific cohort: 1. Diagnosis of anaphylaxis 2. Mild allergic reaction 3. Febrile transfusion reaction 4. Healthy, no known allergic disease Exclusion Criteria: Suspicion or diagnosed sepsis Children

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Biomarkers (platelet activating factor [PAF], anaphylatoxins) and basophil activation test (BAT)
Analysis of biomarkers and basophil activation test

Locations
Country Name City State
Norway Haukeland University Hospital Bergen

Sponsors (1)
Lead Sponsor Collaborator
Haukeland University Hospital

Country where clinical trial is conducted

Norway, 

Outcome
Type Measure Description Time frame Safety issue
Primary Clarify mechanisms for anaphylaxis and establish biomarkers for this syndrome Immunological/nonimmunological mechanism 2 days
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