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Omalizumab Treatment in Venom Immunotherapy With Systemic Reactions

Allergy Clinical Trial

Official title:
Influence of Omalizumab Co-treatment on Honey-bee Venom Immunotherapy Failure Due to Systemic Reactions

Clinical Trial Summary

The purpose of this study is to evaluate if omalizumab co-treatment may allow reintroduction of honey bee venom immunotherapy in patients with immunotherapy treatment failure due to systemic reactions.

Clinical Trial Description

Some honey bee venom allergic patients cannot be treated with venom immunotherapy due to systemic reactions during immunotherapy - immunotherapy failure due to systemic reactions. High basophil allergen sensitivity is a risk factor for venom immunotherapy failure due to systemic reactions. Omalizumab decreases basophil sensitivity. Venom immunotherapy failure patients will be co-treated with omalizumab during another attempt of immunotherapy introduction. Patients will be clinically and immunologically followed up after the introduction. ;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02968394
Study type Interventional
Source The University Clinic of Pulmonary and Allergic Diseases Golnik
Contact Peter Kopac, MD
Phone +386 4 25 69 100
Email peter.kopac@klinika-golnik.si
Status Recruiting
Phase N/A
Start date March 2014
View Details
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