Allergy Clinical Trial
Food allergy is a potentially life threatening condition. The current practice consists of
elimination diet and injectable epinephrine in case of a reaction.
Recently, oral immunotherapy has emerged as a treatment for food allergy in milk eggs and
peanuts.
We conduct an oral immunotherapy program with ~500 patients so far. In this study we intent
to follow patients who completed the program and assess their allergy status and quality of
life.
Food allergy is a potentially life threatening condition. The current practice consists of
elimination diet and injectable epinephrine in case of a reaction.
Recently, oral immunotherapy (OIT) has emerged as an treatment for food allergy in milk eggs
and peanuts. Since 4/2010,a clinical OIT program for milk eggs and peanuts is performed at
the Institute fir Allergy Asthma and Immunology at Assaf Harofeh Medical Center with ~500
patients so far. Patients with IgE-mediated food allergy that are >4 years old are eligible.
In this study we intent to follow patients who completed the program. Patients will fill a
questionnaire regarding current consumption of the allergenic food, adverse reactions
experienced and treatments required including the use of EpiPen. Patients underwent skim
prick tests (SPT) for the allergenic food prior to initiation and treatment and will undergo
SPT again upon entering the study. Blood tests for IgE, IGG4, basophil activation and
cytokines will be obtained.
Patients who are not consuming the allergenic food regularly will undergo an oral food
challenge in clinic.
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Observational Model: Cohort, Time Perspective: Cross-Sectional
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