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NCT05119478 Clinical Trial

Evaluation of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in a Large Cohort

Allergic Rhinitis Clinical Trial

— CYPPOT  

Official title:
Prevalence of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in Occitania

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05119478
Other study ID # RECHMPL21_0612
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 1, 2021
Est. completion date April 1, 2022

Study information
Verified date October 2021
Source University Hospital, Montpellier
Contact Davide CAIMMI, MD
Phone 467336112
Email davide.caimmi@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The aim of the study will be to investigate the prevalence of of sensitization to peach and/or cypress in potato sensitized patients, based on the collection of medical data from patient records consulting in the Allergy Unit of the Arnaud de Villeneuve Hospital. Some Gibberellin-regulated protein (GRP) in fruits and pollens have been identified as allergen, and peach GRP (peamaclein) has recently emerged as a relevant food allergen in cypress pollen-hypersensitive patients. Multiple fruit allergies might be related to cross-reactivity between GRPs. Peamaclein shares 82% identity with snakin-1 from potato. Thus, because of this hight homology the investigators want to determine the prevalence of cosensitization between these 3 allergens potato, peach and cypress.

Recruitment information / eligibility
Status Recruiting
Enrollment 594
Est. completion date April 1, 2022
Est. primary completion date January 1, 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 2 Years to 99 Years
Eligibility Inclusion criteria: - Patients evaluated at the Montpellier University Hospital, Allergy Unit - children and adult with positive skin prick test to potato from february 2013 to december 2015 Exclusion criteria: - Patients under legal protection - Patients under guardianship or under curatorship - Patients not capable of understanding French

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France Uhmontpellier Montpellier

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Montpellier

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Rate of sensitization to peach and/or cypress in potato-sensitized patients Rate of sensitization to peach and/or cypress in potato-sensitized patients day 1
Secondary Rate of of sensitization to peach and/or cypress in potato-sensitized patients Rate of sensitization to peach and/or cypress in potato-sensitized patients (cypress pollen-induced allergic rhinitis or food allergy to peach) day 1
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