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miRNA-155 Assay Before and After Immunotherapy and Probiotics

Allergic Rhinitis Clinical Trial

Official title:
MicroRNA-155 Assay in Childhood Allergic Rhinitis Before and After Combined Sublingual Immunotherapy and Probiotics

Clinical Trial Summary

The investigators aimed to explore miRNA-155 change in response to sublingual immunotherapy (SLIT), probiotics and combined treatment with SLIT and probiotics in AR children.

Clinical Trial Description

Allergic rhinitis (AR) is an inflammatory state characterized by a disturbance of immunoregulatory mechanisms that leads to an amplified T helper "Th-2" response. Micro-RNAs (miRNAs) are short single-stranded RNA molecules that post transcriptionally control gene expression and can mediate allergic process. The aim of this study was to explore miRNA-155 change in response to sublingual immunotherapy (SLIT), probiotics and combined treatment with SLIT and probiotics in AR children. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04603456
Study type Interventional
Source Zagazig University
Contact
Status Completed
Phase Phase 4
Start date September 1, 2018
Completion date May 1, 2019
View Details
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