Allergic Contact Dermatitis Clinical Trial
Official title:
Democratization of Allergy Skin Patch Testing to Increase Efficiency and Scale of the Practice
The purpose of this research is to assess human and artificial intelligence performance in grading contact dermatitis reactions in healthy volunteers.
Study participation involves three visits to the study site on Days 1, 3, and 5, and completion of a demographics and allergy history questionnaire. Researchers will review medical history and current medications. On Day 1 a patch will be applied with 10 allergens and a routine skin examination will be conducted and a photograph will be taken of the forearm. On day 3, subjects will return to remove the patch test and have photographs of the area taken. On day 5, the final assessment for allergic contact dermatitis will be performed and photographs of the area taken. Key Information: The most common side effect of skin testing is slightly swollen, red, itchy bumps (wheals). These wheals may be most noticeable during the test. In some, an area of swelling, redness and itching may develop a few hours after the test and remain for a couple of days. Rarely, allergy skin tests can produce a severe, immediate allergic reaction. The patches are worn on the forearm for 48 hours. During this time, bathing and activities that cause heavy sweating should be avoided. Irritated skin at the patch site may indicate an allergy. If a positive test result is documented, a medical professional will provide education and recommend follow up with primary care provider. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03945760 -
Efficacy of Baricitinib In Treatment of Delayed-Type Hypersensitivity Versus Irritant Skin Reactions in Healthy Adult Male Subjects
|
Early Phase 1 | |
Not yet recruiting |
NCT05498467 -
The Role of Interleukin-1 Beta Targeted Therapy for Patients Suffering From Allergic Contact Dermatitis
|
Phase 3 | |
Active, not recruiting |
NCT03680131 -
Evaluation of EB01 Cream for the Treatment of Chronic Allergic Contact Dermatitis
|
Phase 2 | |
Recruiting |
NCT05535738 -
Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation
|
Phase 2/Phase 3 | |
Recruiting |
NCT06191627 -
Patient Experience and Quality of Patch Testing on the Legs vs Back
|
N/A | |
Completed |
NCT00867607 -
Safety, Tolerability, and Efficacy of 21 Days Dermal Application of MRX-6 on Mild to Moderate Contact Dermatitis
|
Phase 1/Phase 2 | |
Recruiting |
NCT00445029 -
Pathophysiological Study of Allergic Contact Dermatitis to Para-Phenylenediamine (PPD). Analysis of Cellular and Molecular Targets in Skin Inflammation
|
N/A | |
Completed |
NCT04365140 -
MicroRNA-126 and Its Target VCAM-1Dermatitis to Nickel
|
||
Recruiting |
NCT05991674 -
A Prospective Study to Investigate Contact Sensitization Using Classic and Machine Learning Techniques
|
||
Completed |
NCT00931242 -
Study of Apremilast in Atopic or Contact Dermatitis
|
Phase 2 | |
Completed |
NCT01798589 -
Bioequivalence of Ethylenediamine Dihydrochloride Study
|
Phase 4 | |
Completed |
NCT01546298 -
Immune Reactions in Contact Dermatitis Affected Skin
|
||
Recruiting |
NCT03935971 -
The Effects of Dupilumab on Allergic Contact Dermatitis
|
Phase 4 | |
Completed |
NCT01797562 -
Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents
|
N/A | |
Not yet recruiting |
NCT05858723 -
Repeated Open Application Test (ROAT) Study With Hydroperoxides of Linalool
|
N/A | |
Completed |
NCT02534441 -
Epidemiology and Co-Reactivity of Novel Surfactant Allergens
|
N/A | |
Not yet recruiting |
NCT01413477 -
Nickel Desensitization Using Topical Therapy
|
N/A | |
Completed |
NCT00133341 -
Clinical Evaluation of the 3 Allergens: Methyldibromoglutharonitrile, Parthenolide and Goldnatriumthiosulphate
|
Phase 2 | |
Completed |
NCT00132600 -
Clinical Evaluation of Bacitracin
|
Phase 2 | |
Completed |
NCT03902392 -
Red Grape Polyphenol Oral Administration to Women Affected by Nickel-mediated Allergic Contact Dermatitis
|
N/A |