Bronchial Allergen Provocation Tests in Asthmatics in Guangzhou

Status Completed

Clinical Trial Summary

The purpose of this study is to establish the methodology of bronchial provocation tests with house dust mites in China, and to evaluate its safety and effects on upper and lower airways inflammation.

Clinical Trial Description

After screening,each participant undergo baseline lung function test,airway inflammation evaluation (blood and sputum eosinophils count,interleukin-13 (IL-13),FeNO)and airway responsiveness tests(methacholine bronchial provocation,nasal histamine provocation).

On the second day,the participant undergo bronchial house dust mites challenge tests.

On the third day,the participant undergo the lung function test,airway inflammation evaluation (blood and sputum eosinophils count,IL-13,FeNO)and airway responsiveness tests(methacholine bronchial provocation,nasal histamine provocation). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02504528
Study type	Interventional
Source	Guangzhou Institute of Respiratory Disease
Contact
Status	Completed
Phase	N/A
Start date	July 1, 2015
Completion date	February 1, 2018

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