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The Tolerability and Effects of AZD0530 in Individuals With or Without a Family History of Alcoholism

Alcoholism Clinical Trial

Official title:
A Phase One Study Investigating the Tolerability and Effects of AZD0530 on Functional Neuroimaging Responses in Individuals With or Without a Family History of Alcoholism

Clinical Trial Summary

Functional neuroimaging of alcoholism vulnerability: glutamate, reward, impulsivity, and Pavlovian-to-instrumental transfer (PIT), part II Saracatinib

Clinical Trial Description

To assess the effect of oral AZ D0530 at various doses on neuroimaging parameters associated with various forms of impulsivity mediated through glutamate-dopamine interactions, as ascertained through functional magnetic resonance imaging. -- --NOTE-- AZD0530 dosage of 50mg was discontinued by manufacturer. Adjustments were made to account for the removal of the 50mg dosage in all arms of the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02262026
Study type Interventional
Source Yale University
Contact
Status Completed
Phase Phase 1
Start date November 1, 2014
Completion date April 26, 2019
View Details
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