N-acetylcysteine Plus Naltrexone for the Treatment of Alcohol Dependence

Status Completed

Clinical Trial Summary

The purpose of this study is to determine whether: (1) the combination of N-acetylcysteine + high-dose naltrexone (150 mg) works better than high-dose naltrexone (150 mg) alone in reducing alcohol drinking; and (2) high-dose naltrexone (150 mg) alone works better than low-dose naltrexone (50 mg) alone in reducing alcohol drinking.

Clinical Trial Description

The 3 groups (N-acetylcysteine plus naltrexone 150 mg, naltrexone 150 mg, and naltrexone 50 mg) will be compared in a 12-week randomized, double-blind clinical trial. ;

Study Design

Related Conditions & MeSH terms

Alcoholism

Clinical Trial Details

NCT number	NCT01214083
Study type	Interventional
Source	VA Office of Research and Development
Contact
Status	Completed
Phase	Phase 2
Start date	October 15, 2010
Completion date	October 30, 2016

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