Alcohol-Related Disorders Clinical Trial
Official title:
The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)
This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.
This study is a placebo-controlled, randomized, double blind, clinical trial to investigate the safety, tolerability and efficacy of the psychedelic dimethyltryptamine (DMT), in addition to a short course of psychotherapy, on Alcohol Use Disorder (AUD). The investigators hypothesize that relative to control (0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion plus psychotherapy), a single psychedelic dose of DMT (plus psychotherapy) in individuals with AUD will 1) be safe and 2) well-tolerated, and 3) reduce alcohol consumption measured in the laboratory the day after, and over the following 8 weeks. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02911077 -
Longitudinal Changes in the Oral and Gut Microbiome of Individuals With Alcohol Dependence
|
||
Completed |
NCT04473482 -
Michigan Alcohol Improvement Network- Alcohol Reduction and Treatment Trial
|
N/A | |
Completed |
NCT03340051 -
Remote Alcohol Monitoring and Episodic Thinking
|
N/A | |
Withdrawn |
NCT04659278 -
Endourage Complete Spectrum Oral Mucosal Drops (OMD) in Adults Desiring a Reduction in Ethanol Use
|
N/A | |
Completed |
NCT02829970 -
Helping College Students With ADHD Lead Healthier Lifestyles
|
N/A | |
Completed |
NCT02388243 -
The Computer-based Drug and Alcohol Training Assessment in Kenya
|
N/A | |
Completed |
NCT00248612 -
Psychosocial and Medication Treatment for Anxiety in Alcoholism
|
Phase 2/Phase 3 | |
Recruiting |
NCT03535129 -
A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
|
N/A | |
Completed |
NCT00142844 -
Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1
|
Phase 2 | |
Completed |
NCT00000257 -
Effects of Alcohol History on Effects of Nitrous Oxide - 9
|
N/A | |
Completed |
NCT00000278 -
Disulfiram for Cocaine-Alcohol Abuse - 3
|
Phase 2 | |
Recruiting |
NCT06074341 -
TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study
|
N/A | |
Not yet recruiting |
NCT05910580 -
Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years
|
N/A | |
Completed |
NCT02655354 -
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity
|
N/A | |
Completed |
NCT01344122 -
Medication-Assisted Treatment Implementation in Community Correctional Environments (MATICCE)
|
N/A | |
Completed |
NCT01227980 -
Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism in Anxious Alcoholics^
|
Phase 2 | |
Completed |
NCT00400010 -
Alcohol Expert System Intervention for Problematic Alcohol Use
|
N/A | |
Completed |
NCT00391742 -
Stepped Interventions for Problem Drinkers
|
N/A | |
Completed |
NCT04725552 -
Identifying and Managing Alcohol-related Health Problems in General Practice
|
N/A | |
Completed |
NCT02968186 -
Implementing Screening and Brief Interventions for Excessive Drinkers in Primary Health Care
|
N/A |