Intranasal Oxytocin for the Treatment of Alcohol Use Disorder

Status Recruiting

Clinical Trial Summary

Primary: The primary objective of the study is to compare the efficacy of intranasal oxytocin in reducing the weekly percentage of heavy drinking days over the 10 weeks of maintenance treatment among subjects with moderate to severe Alcohol Use Disorder (AUD). A "heavy drinking day" is 4 or more drinks per drinking day for women and 5 or more drinks per drinking day for men. Secondary: Secondary objectives include assessment of other measures of the effects of oxytocin compared with placebo on reduction of alcohol use as well as effects on psychological assessments, alcohol craving, alcohol-related consequences, cigarette smoking and other nicotine use, retention in the study, safety, and application site (nares) tolerability throughout the study.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03878316
Study type	Interventional
Source	National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Contact	Megan Ryan, MBA
Phone	3014434225
Email	mryan1@nih.gov
Status	Recruiting
Phase	Phase 2
Start date	May 5, 2022
Completion date	March 2024

View Details

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