Effects of Alcoholic Beverages in Pro-inflammatory and Antioxidant Profile After an Oral Fat Diet

Alcohol Consumption Clinical Trial

Official title:

Effects of Acute and Chronic Red Wine Intake in the Expression of Pro-inflammatory and Prothrombotic Factors in Circulating Monocytes

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02033174
• Other study ID #: AlcoholInfl_IiSGM_2000
• Secondary ID: FIS01/0602
• Status: Completed
• Phase: N/A
• First received: January 9, 2014
• Last updated: January 9, 2014
• Start date: January 2001
• Est. completion date: July 2001

Study information

• Verified date: January 2014
• Source: Instituto de Investigación Sanitaria Gregorio Marañón
• Contact: n/a
• Is FDA regulated: No
• Health authority: Spain: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

Hypothesis: Red wine intake but not other alcoholic beverages together with a fat diet will decrease inflammatory factors and lipid peroxidation and decrease antioxidant capacity in healthy people after a five days period.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: July 2001
• Est. primary completion date: July 2001
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• Healthy volunteers

Exclusion Criteria:

• Individuals with a plasma cholesterol level > 220 mg/dl

• Smokers

Study Design

Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Alcohol Consumption
• Alcohol Drinking

Intervention

Other:
• Alcoholic beverages

• Oral fat diet

Locations

Country	Name	City	State
Spain	IiSGM	Madrid

Sponsors (1)

Lead Sponsor	Collaborator
Instituto de Investigación Sanitaria Gregorio Marañón

Country where clinical trial is conducted

Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change of baseline in concentrations of pro inflammatory factors and antioxidant capacity in plasma		5 days	No