AL Amyloidosis Clinical Trial
Official title:
Phase III Trial of High-dose Melphalan and Stem Cell Transplantation Versus High-dose Melphalan and Bortezomib and Stem Cell Transplantation in Patients With AL Amyloidosis
Standard treatment for AL Amyloidosis is high-dose melphalan and stem cell transplant.
This study will compare the safety and effectiveness of standard treatment with high-dose
melphalan and stem cell transplant, compared with investigational bortezomib when used in
combination with standard treatment with high-dose melphalan and stem cell transplant for AL
amyloidosis.
This study seeks to enroll patients with AL amyloidosis who have been recommended for
standard treatment with high-dose melphalan and stem cell transplant.
Standard treatment for this disease is high-dose melphalan and stem cell transplant.
The purpose of this study is to compare the safety and effectiveness of standard treatment
with high-dose melphalan and stem cell transplant, compared with investigational bortezomib
when used in combination with standard treatment with high-dose melphalan and stem cell
transplant for AL amyloidosis.
Patients enrolled in this study will receive either standard treatment with high-dose
melphalan and stem cell transplant, or investigational bortezomib used in combination with
standard treatment with high-dose melphalan and stem cell transplant.
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