Airway Complications Clinical Trial
Official title:
Optimal End-Tidal Concentration of Sevoflurane and Desflurane for Removal of Supreme Laryngeal Mask Airway in Anaesthetized Adults
The purpose of this study is to determine the optimal volatile anaesthetic (sevoflurane and
desflurane) to remove a Supreme LMA in adults in which there is minimal airway response.
Null hypothesis: there is no significant difference between the optimal end tidal
concentration of sevoflurane and desflurane for Supreme LMA removal.
The manufactures' instructions for removal of the LMA recommend waiting until protective
reflexes have returned. However, the appropriate timing for removal remains controversial. A
more frequent incidence of airway hyperreactivity and complications has been reported by
some studies when the LMA was removed in the awake state versus the anesthetized state.
Techniques that reduce the time from LMA removal to the return of protective airway reflexes
would minimize the risk of aspiration, contamination, or airway obstruction.
With increasingly common use of Supreme LMA in anaesthetic practice, a safe and suitable
depth for removal of the Supreme LMA requires research.
Thus the determination of the optimal end-tidal concentration of commonly used volatile
agents ie. Sevoflurane and Desflurane for Supreme LMA removal requires research, both for
patient safety and minimising anaesthetic costs in dealing with airway complications.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Supportive Care
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02743767 -
Frequency of Airway Complications During General Anaesthesia After Introducing Five Handling Adaptations
|
N/A |