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NCT02674516 Clinical Trial

The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

Aggression Clinical Trial

Official title:
The Effect of Repeated Transcranial Direct Current Stimulation of the Prefrontal Cortex on Antisocial and Aggressive Behavior

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02674516
Other study ID # 823967
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date January 2016
Est. completion date June 2021

Study information
Verified date January 2022
Source University of Pennsylvania
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study investigates the relationship between prefrontal cortex activity and antisocial and aggressive behavior, and risk factors for such behavior. In the double-blind, randomized controlled trial, participants will undergo three sessions of anodal transcranial direct current stimulation of the dorsolateral prefrontal cortex or sham stimulation and complete survey and laboratory measures assessing antisocial behavior and risk factors. Heart rate and skin conductance will also be measured.

Recruitment information / eligibility
Status Completed
Enrollment 32
Est. completion date June 2021
Est. primary completion date June 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Above 18 years of age - Able to understand the nature of the study and give informed consent Exclusion Criteria: - Currently consuming anti-convulsant, anti-psychotic, or sedative/hypnotic medications - Currently consuming anti-depressants - History of seizures - Metallic implants on the scalp - Participation in other transcranial magnetic stimulation (TMS) or tDCS experiments on the same day - History of adverse reactions to tDCS

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Transcranial direct current stimulation

• Sham transcranial direct current stimulation

Locations
Country Name City State
United States University of Pennsylvania Philadelphia Pennsylvania

Sponsors (1)
Lead Sponsor Collaborator
University of Pennsylvania

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of Pins Inserted Into a Virtual Voodoo Doll After 48 Hours The number of pins (between 0 and 51) that participants decide to insert into a picture of a voodoo doll on a computer that represents either a romantic partner or close friend will be recorded. On average, 48 hours after the first 20-minute tDCS or sham session ends
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