Aggression Clinical Trial
Official title:
Aggressive Behavior Induced by SSRIs During the First Month of Treatment
SSRIs are the first line of therapy for anxiety and depressive disorders and for many other
clinical diagnoses. One of the most disturbing side effects that is observed is a tendency
towards aggressiveness among patients receiving medications from this group, mainly during
the first month of therapy. Aggressive behavior tends to occur in some individuals but not in
others. In some sub-groups of people, personality and character traits might make a person
more prone to aggressive behavior.
In this study the investigators try to estimate the tendency towards aggressive behavior in
patients prescribed to a medication from the SSRI group. By using a comparative computer
simulation they hope to be able to detect delicate changes and to maybe get some clues of the
personalities prone to aggressive behavior in the future.
Selective serotonin reuptake inhibitors (SSRIs) became the first line therapy for anxiety and
depressive disorders and for many other clinical diagnoses. One of the most disturbing side
effects that is observed is a tendency towards aggressiveness among patients receiving
medications from this group, mainly during the first (one month) period of therapy.
Aggressive behavior tends to occur in some individuals but not in others. Until now most of
the cases and reports in the literature demonstrate the extreme events of aggressive
behavior. These personality or any other character traits that are more prone to develop
aggressiveness have not been studied and it is not clear if this side effect manifests itself
just in the extreme rare cases or if it is a more common phenomenon that occurs in a wider
group of people.
In this study we try to estimate the tendency towards aggressive behavior of patients
prescribed to a medication of the SSRI group. By using a comparative computer simulation we
hope to be able to detect more delicate changes and maybe to get some clues of the
personalities prone to aggressive behavior in the future.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02485587 -
Arousal-Biofeedback for the Treatment of Aggressive Behavior in Children and Adolescents
|
N/A | |
| Completed |
NCT02552147 -
Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism
|
Phase 1 | |
| Active, not recruiting |
NCT01792167 -
Multi-Site Evaluation of Second Step
|
N/A | |
| Completed |
NCT00455234 -
Rapid Tranquillization Trial: TREC-India II
|
Phase 3 | |
| Completed |
NCT00000385 -
Long-Term Lithium Treatment for Aggressive Conduct Disorder
|
Phase 3 | |
| Not yet recruiting |
NCT03672942 -
Communication Skills vs. Mindfulness for IPV
|
N/A | |
| Recruiting |
NCT04732052 -
The Use of Transcranial Direct Current Stimulation (tDCS) in Adults With Developmental Disabilities
|
N/A | |
| Terminated |
NCT02483572 -
Treatment of Severe Destructive Behavior: FCT Versus Wait-List Control
|
N/A | |
| Completed |
NCT04097431 -
Identifying Precursors to Severe Problem Behavior
|
N/A | |
| Completed |
NCT04130360 -
A Trial of an Online Problem-solving Intervention for Aggression
|
N/A | |
| Completed |
NCT02563145 -
Real-time fMRI for the Treatment of Aggressive Behavior in Adolescents
|
N/A | |
| Completed |
NCT00510094 -
Effectiveness of Treatment for Relational Aggression in Urban African American Girls
|
Phase 3 | |
| Recruiting |
NCT03430973 -
Aggressive Driving and Road Rage: A Driving Simulation Experiment.
|
N/A | |
| Completed |
NCT03693209 -
Using Implementation Intentions to Reduce Anger and Aggression in Adolescence
|
N/A | |
| Recruiting |
NCT05543681 -
IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's
|
Phase 2 | |
| Completed |
NCT03784846 -
Mindfulness-Based Resilience Training for Aggression, Health, and Stress Among Law Enforcement Officers
|
N/A | |
| Active, not recruiting |
NCT04204759 -
Transcranial Direct Current Stimulation and Antisocial Behavior
|
N/A | |
| Completed |
NCT06453070 -
Hasan Kalyoncu University
|
||
| Completed |
NCT01965184 -
Cognitive-Behavioral Therapy for Disruptive Behavior in Children and Adolescents
|
N/A | |
| Completed |
NCT04625465 -
Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence
|
N/A |