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Aggression clinical trials

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NCT ID: NCT03210662 Active, not recruiting - Clinical trials for Refractory Non-Hodgkin Lymphoma

Pembrolizumab and External Beam Radiation Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Start date: November 1, 2017
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well pembrolizumab and external beam radiation therapy work in treating patients with non-Hodgkin lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving pembrolizumab and external beam radiation therapy may work better in treating patients with non-Hodgkin lymphoma than pembrolizumab alone.

NCT ID: NCT03161054 Completed - Clinical trials for Aggressive Non-Hodgkin Lymphoma

Metronomic Chemotherapy in Elderly Non-fit Patients With Aggressive B-Cell Lymphomas

Start date: September 12, 2017
Phase: Phase 2
Study type: Interventional

This is a phase II study of metronomic chemotherapy in elderly non-fit patients (>65 years) with aggressive B-Cell lymphomas

NCT ID: NCT03159468 Completed - Heavy Drinking Clinical Trials

Emotion Regulation Interventions for Alcohol-Related Sexual Aggression

Start date: December 31, 2016
Phase: N/A
Study type: Interventional

Rates of sexual assault are alarmingly high, and alcohol is consistently implicated in the majority of these assaults. Despite well-intentioned prevention efforts, this pandemic continues unabated, warranting the development of novel and innovative approaches to the reduction of sexual aggression. The goal of this research is to evaluate the efficacy of two brief online emotion regulation interventions for reducing alcohol-related sexual aggression in heavy episodic drinking young men with a sexual aggression history. Previous research suggests that emotion regulation difficulties are associated with both alcohol consumption and aggressive behavior. Despite the potential prevention utility of improving sexually aggressive men's emotion regulation skills in order to reduce their alcohol-related sexual aggression, this approach has yet to be explored. Thus, this study evaluates the effects of two brief online ER interventions - cognitive restructuring and mindfulness - on men's emotion regulation during a sexual aggression-related analogue. Additionally, these effects will be evaluated during both sober and intoxicated states through a laboratory- based alcohol administration experiment.

NCT ID: NCT03142776 Completed - Clinical trials for Aggressive Periodontitis, Generalized

Nonsurgical Periodontal Treatment Associated or Not With Systemic Antibiotics and Photodynamic Therapy

Start date: March 2014
Phase: N/A
Study type: Interventional

To assess the local effect of the antimicrobial therapy using clarithromycin association with photodynamic therapy (PDT) in the treatment of generalized aggressive periodontitis (GAgP).

NCT ID: NCT03140059 Active, not recruiting - Clinical trials for Aggressive Periodontitis, Generalized

Comparison Between Surgical Access and Repeated Applications of APDT

Start date: June 2016
Phase: N/A
Study type: Interventional

The aim of this study will be to compare the approach of repeated applications of APDT versus surgical therapy for the treatment of residual pockets in generalized agressive periodontitis.

NCT ID: NCT03139110 Completed - Mediation Clinical Trials

Impact of a Mediator for Patient Intake in Emergency Departments

MEDIA
Start date: November 15, 2017
Phase:
Study type: Observational

Violence in the workplace is becoming a serious phenomenon in the contemporary world of work. Hospital staff, like any employee working in contact with the public, is particularly exposed to this violence. In emergency departments, the number of patients treated and their heterogeneity, the problems of communicating with healthcare professionals, and waiting times, favor conflict situations. In the already tense context of the emergencies, the incivilities or violent acts have an impact on the well-being of professionals. In order to prevent these situations of violence, a solution could be to integrate a professional with specific skills into the teams to perform mediation functions between caregivers and patients. The aim of the study is to evaluate the impact of the presence of a mediator in emergency services on personal (verbal or physical) attacks on professionals (caregivers, doctors, administrative staff).

NCT ID: NCT03132805 Completed - Aggression Clinical Trials

An Evaluation of an Integrated Approach to Prevention and Early Intervention in the Elementary School Years

P2P+IY
Start date: June 1, 2016
Phase: N/A
Study type: Interventional

In this study, the investigators propose to examine whether the combination of a universal, elementary school-based preventive intervention with an indicated preventive and treatment intervention would yield greater impact on aggression than the universal preventive intervention alone.

NCT ID: NCT03132714 Completed - Clinical trials for Aggressive Periodontitis, Generalized

Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis

Start date: March 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this project is to compare the efficacy and the local effect of the association of single or repeated application of photodynamic therapy (PDT) with antibiotic agents using Amoxicillin + Metronidazole or Clarithromycin in the treatment of patients with Generalized Aggressive Periodontitis (GAgP).

NCT ID: NCT03118947 Completed - Clinical trials for Agitation and Aggression in Alzheimer's Disease

A Study of Pimavanserin for the Treatment of Agitation and Aggression in Subjects With Alzheimer's Disease

Start date: February 23, 2017
Phase: Phase 2
Study type: Interventional

To evaluate the safety and tolerability of pimavanserin over 52 weeks of treatment in subjects with probable AD who have symptoms of agitation and aggression

NCT ID: NCT03095066 Completed - Clinical trials for Neurobehavioral Disinhibition

Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Participants With Traumatic Brain Injury

Start date: May 30, 2017
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, placebo-controlled study to evaluate AVP-786 for the treatment of neurobehavioral disinhibition including aggression, agitation, and irritability in participants with traumatic brain injury (TBI).