Clinical Trial Details
— Status: Completed
Administrative data
NCT number |
NCT05164679 |
Other study ID # |
Knoglestaerk |
Secondary ID |
|
Status |
Completed |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
January 4, 2019 |
Est. completion date |
July 9, 2019 |
Study information
Verified date |
December 2021 |
Source |
University of Copenhagen |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
To minimize fracture risk, diverse and varied training of high intensity (multimodal
training) is recommended to increase bone strength. However, the effectiveness of different
training programmes performed in community settings remain uncertain. The present study aimed
to evaluate the feasibility and the effectiveness of 19-week of multimodal training in a
local community center in Copenhagen, Denmark. The health promotion initiative had special
emphasis on musculoskeletal health in postmenopausal women.
Description:
A local community center was offering supervised multimodal training (MMT) to postmenopausal,
healthy women twice weekly, and the aim of the present study was to evaluate the feasibility
and the musculoskeletal health promoting effects of the training. The evaluation study lasted
for 19 weeks, and the average attendance rate of MMT participants had to be > 1 hour weekly.
The primary outcomes were bone mineral density (BMD) assessed by Dual-Energy X-ray
Absorptiometry (DXA) scanning and the fasted plasma concentration of bone turnover markers
(BTM): N-terminal propeptide of type I procollagen (P1NP) , C-terminal telopeptide of type I
collagen (CTX), Osteocalcin), while secondary outcomes were body composition variables,
dynamic postural balance and functional muscle strength. To test within- and between-group
differences in the pre and post outcomes the training group (MMT) was compared with a
sedentary control group (CON).
Every participant was fully informed before giving her written informed consent to the
procedures and potential discomfort associated with the study. The study was conducted in
accordance with the Declaration of Helsinki and approved by the local ethics committee of the
Capital Region of Denmark, H-18044190.