Mild Cognitive Impairment Clinical Trial
Official title:
Arizona Alzheimer's Disease Core Center
The main objective of this research project is to provide a comprehensive clinical database
of patients with Alzheimer's disease (AD) and other forms of dementia, individuals with mild
cognitive impairment (MCI), and age-matched normal controls. The study will also attempt to
identify cognitively normal individuals at genetically defined risk for Alzheimer's disease
through genetic screening.
All participants are seen annually. Autopsies to establish diagnoses in patients with
dementia, patients with mild MCI, and cognitively normal elderly control subjects will also
be conducted.
All participants are seen annually. In addition to a detailed neurological examination, participants will receive a standardized battery of neuropsychological tests and will undergo genetic testing. The investigators will provide standardized periodic longitudinal assessment of the research participants. Autopsies to establish neurohistopathological diagnoses in clinically well-characterized patients with dementia, patients with mild MCI, and cognitively normal elderly control subjects will also be conducted. ;
Observational Model: Cohort, Time Perspective: Prospective
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