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Clinical Trial Summary

The goal of this clinical trial is to learn if the areas of stressed cells in the retina correlate to areas of disease identified in standard imaging and whether the images are helpful to identify potential areas of concern before symptoms or disease occurs. The main question it aims to answer is: - to evaluate patterns of increased autofluorescence FPF in the setting of geographic atrophy Participants will undergo FPF imaging using the OcuMet Beacon system.


Clinical Trial Description

The goal of this clinical trial is to learn if areas of mitochondrial functional distress in the macula (as imaged using fundus flavoprotein fluorescence) correlate with areas of anatomic disease identified on standard fundus autofluorescence (FAF) imaging. The study aims to evaluate patterns of anomalous fundus flavoprotein fluorescence (FPF) in patients with advanced geographic atrophy (GA) due to dry age-related macular degeneration. Participants will undergo FPF imaging using the OcuMet Beacon system and FAF imaging using Heidelberg Spectralis. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06381596
Study type Interventional
Source University of Wisconsin, Madison
Contact Amy Remm
Phone 608-262-3377
Email amy.remm@wisc.edu
Status Recruiting
Phase N/A
Start date April 16, 2024
Completion date April 2025

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