Clinical Trials Logo
  1. Home
  2. Age-Related Macular Degeneration
  3. NCT03407274

Flavonoids and Age-related Macular Degeneration

Age-Related Macular Degeneration Clinical Trial

Official title:
Dietary Flavonoids and the Prevalence and 15-year Incidence of Age-related Macular Degeneration in the Blue Mountains Eye Study

Clinical Trial Summary

This study uses 15-year data from the Blue Mountains Eye Study to establish independent associations between dietary intake of total flavonoids and common flavonoid classes with the prevalence and 15-year incidence of age-related macular degeneration (AMD), independent of potential confounders.

Clinical Trial Description

We aimed to use a well characterized large cohort of adults aged 49+ years ( Blue Mountains Eye Study participants) to establish: 1) Associations between dietary intake of total flavonoids with the prevalence and 15-year incidence of age-related macular degeneration (AMD), independent of potential confounders; 2) Prospective relationship between six common flavonoid classes (flavonols, flavan-3-ols, flavones, flavanones, anthocyanins, and isoflavones) and key individual flavonoids (quercetin and hesperidin) with the prevalence and 15-year incidence of AMD; and 3) associations between the main foods and beverages contributing to total flavonoids e.g. tea, apples, oranges and orange juice, and both the prevalence and 15-year incidence of AMD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03407274
Study type Observational
Source University of Sydney
Contact
Status Completed
Phase N/A
Start date January 1992
Completion date December 2009
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05984927 - NG101 AAV Gene Therapy in Subjects With Wet Age-Related Macular Degeneration Phase 1/Phase 2
Active, not recruiting NCT05536297 - Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy Phase 3
Recruiting NCT04101604 - Biomarkers of Common Eye Diseases
Completed NCT04005352 - Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON) Phase 3
Withdrawn NCT02873351 - A Safety and Efficacy Study of Carbidopa-levodopa in Patients With Macular Degeneration Phase 2
Active, not recruiting NCT02802657 - Efficacy and Safety of "Treat-and-Extend" Regimen Versus "Pro Re Nata" of Conbercept in Age-related Macular Degeneration Phase 4
Not yet recruiting NCT02864472 - Comparison of PDT Combination With Ranibizumab vs. Ranibizumab Monotherapy in Persistent PCV With Initial Loading Dose Phase 4
Recruiting NCT01521065 - An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration Phase 2
Completed NCT01445548 - Sirolimus for Advanced Age-Related Macular Degeneration Phase 1/Phase 2
Completed NCT02035722 - Intravitreal Injections-related Anxiety Phase 2/Phase 3
Completed NCT01175395 - 20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD) Phase 1/Phase 2
Recruiting NCT01048476 - Effects of Lutein and Zeaxanthin Supplementation on Age-related Macular Degeneration Phase 1/Phase 2
Active, not recruiting NCT01174407 - Implication of CD35, CD21 and CD55 in Exudative Age-related Macular Degeneration N/A
Terminated NCT00712491 - Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration Phase 1/Phase 2
Completed NCT00345176 - Age-Related Eye Disease Study 2 (AREDS2) Phase 3
Completed NCT02140151 - Prophylactic Ranibizumab for Exudative Age-related Macular Degeneration Phase 1/Phase 2
Completed NCT02555306 - A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration Phase 1/Phase 2
Recruiting NCT04796545 - Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration N/A
Completed NCT03166202 - Age-Related Macular Degeneration, Scotopic Dysfunction, and Driving Performance in a Simulator
Completed NCT01397409 - Evaluation of AGN-150998 in Exudative Age-related Macular Degeneration (AMD) Phase 2