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Age-Related Macular Degeneration clinical trials

View clinical trials related to Age-Related Macular Degeneration.

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NCT ID: NCT05447650 Recruiting - Clinical trials for Age-Related Macular Degeneration

Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)

i-SIGHT
Start date: April 12, 2022
Phase: N/A
Study type: Interventional

Evaluate the safety and efficacy of transpalpebral microcurrent stimulation (MCS) therapy for patients with nonexudative (dry) age-related macular degeneration (AMD).

NCT ID: NCT05441072 Completed - Clinical trials for Diabetic Retinopathy

Validation of Bulbicam for DR- and AMD-patients

Start date: December 19, 2022
Phase:
Study type: Observational

Aim - To investigate repeatability and stability of the six OTH-related Bulbicam tests in patients suffering from a) Diabetic retinopathy (DR), b) Age related macular degeneration (AMD) and matched healthy controls (HC). - To compare Bulbicam and the Standard Method on measurements of Visual Field and Pupil - To contribute to the establishment of normal range for DR and AMD patients with different degree in the disease development related to the Bulbicam tests. - To contribute to the establishment of normal range for a normal population without eye-disease related to the Bulbicam tests. Study population The study consists of the following three study populations: 1) Patients suffering from DR of both genders above 18 years of age with different disease degree; 2) Patients suffering from AMD of both genders above 18 years of age with different disease degree; 3) Gender- and age-matched HC without any eye diseases. Study procedure Participants, who fulfil the inclusion criteria; do not meet any of the exclusion criteria and willing to give informed consent to participate will receive an appointment for starting the study. The Bulbicam examination will be performed twice a day with a rest period of one hour between each registration. This procedure will be repeated the following two days. All demographic data, social factors and history of disease will be recorded at screening. Additionally, the quality of life (QoL) questionnaires EQ-5D-5L developed by EuroQol will be recorded initially as individual baseline values. The Common Terminology Criteria for Adverse Events (CTCAE) version 4.0 will be used for measuring and classifying the tolerability and toxicity at the end of each day of investigation.

NCT ID: NCT05438732 Recruiting - Clinical trials for Age-Related Macular Degeneration

Multicenter Clinical Study of the SING-IMT in Patients With Late-stage AMD

CONCERTO
Start date: June 16, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to determine the safety and effectiveness of the smaller incision, new generation (SING), implantable miniature telescope (IMT) in patients with moderate-severe central vision loss due to late-stage age-related macular degeneration (AMD).

NCT ID: NCT05437302 Completed - Clinical trials for Age-Related Macular Degeneration

Effectiveness of Prism Spectacles in Patients With Age Related Macular Degeneration

Start date: October 4, 2021
Phase: N/A
Study type: Interventional

A study is conducted to determine the effectiveness of prism spectacles in improving visual acuity with age related macular degeneration patients and to assess the improvement in quality of life in patients by using prism spectacles.

NCT ID: NCT05433766 Enrolling by invitation - Clinical trials for Age-Related Macular Degeneration

Patient-centred Smartphone AI for Protecting Vision in Macular Disease

Start date: March 8, 2023
Phase:
Study type: Observational

Macular disease is the leading cause of blindness in the UK and age-related macular degeneration must undergo monitoring to determine if an injection into the eye is required that month [required in 50% of visits] - these patients are the 'frequent fliers' within ophthalmology units, visiting specialist hospital clinics on a monthly or bi-monthly basis. This project aims to create a home-monitoring algorithm that could in the future, enable the movement of 'monitoring' of chronic eye disease into the patients' homes: remotely identifying who does need an in-person appointment, and who can safely stay away from hospital.

NCT ID: NCT05427994 Completed - Clinical trials for Age-Related Macular Degeneration

Assessing the Quality of Life and Social Support in Age-Related Macular Degeneration Patients

Start date: April 5, 2021
Phase:
Study type: Observational

The aim of this study is to evaluate the quality of life of AMD patients related to vision using the short version of the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), patients' social support, and their relationship with demographic and clinical variables.

NCT ID: NCT05391074 Active, not recruiting - Clinical trials for Age-Related Macular Degeneration

Oral Postbiotics in Patients With Macular Atrophy

REVERS-GA
Start date: December 1, 2020
Phase: N/A
Study type: Interventional

A pilot study to evaluate the safety and efficacy of oral therapy with Postbiotics in patients with geographic atrophy secondary to age-related macular degeneration, myopia, or angioid streaks.

NCT ID: NCT05390840 Recruiting - Clinical trials for Age-Related Macular Degeneration

A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD)

Start date: August 9, 2022
Phase: Phase 2
Study type: Interventional

A 2 parts Phase II study to investigate the effect on central macular thickness of treatment with MG-O-1002 eye drops in participants aged over 45 with neovascular age-related macular degeneration (nAMD)

NCT ID: NCT05380492 Active, not recruiting - Clinical trials for Age-related Macular Degeneration

Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Start date: November 17, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This safety study comprises a dose escalation study of VOY-101, followed by a cohort of subjects randomized to the maximum tolerated dose arm, a lower dose arm, and control arm.

NCT ID: NCT05355415 Recruiting - Clinical trials for Age-Related Macular Degeneration

Adaptive Optics Imaging of Outer Retinal Diseases

Start date: August 27, 2021
Phase:
Study type: Observational

The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor, retinal pigment epithelium (RPE), basement membrane or choroidal pathologies) to develop new diagnostic methods, biomarkers, and clinical endpoints.