Age-related Cognitive Decline Clinical Trial
Official title:
MRI and Decline of Aging Aviator Performance
The primary purpose of this study is to apply state-of-the-art Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopic Imaging (MRSI) techniques to measure changes over time in the brain.
We expect that MRI and MRSI techniques will be a useful adjunct in research efforts to
understand individual differences in performance of a complex attention-demanding task, such
as flying a plane or driving a car. Other predictors of change in performance of a complex
task may include simple tests of processing speed and working memory, past training and
recent practice of the task, and genetic risk factors for degenerative brain disease. In
this project, we will examine whether baseline MR measures are as useful as longitudinal MR
measures in predicting amount of change over time in task performance.
This research is part of a long-term effort to achieve earlier identification of individuals
at risk of decline and ultimately minimize loss of function.
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