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Age-associated Memory Impairment clinical trials

View clinical trials related to Age-associated Memory Impairment.

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NCT ID: NCT05934344 Recruiting - Clinical trials for Mild Cognitive Impairment

Effectiveness of an Intervention Using Observation/Action Therapy Among Patients With Mild Cognitive Impairment

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Mild cognitive impairment (MCI) is a transitional state between normal aging and early dementia, characterized by memory deficits without functional impairment. Cognitive decline prevalence is increasing in older adults, impacting independence and quality of life. Motor dysfunctions, often overlooked in MCI, contribute to these limitations. Action Observation Therapy (AOT), a rehabilitation approach involving observing and imitating motor gestures, promotes brain plasticity through the mirror neuron system. While AOT has shown effectiveness in various populations, its application in MCI is understudied. This study aims to investigate the effects of AOT on cognition, upper and lower limb function, daily activities, gait, and balance in MCI patients. It also compares outcomes when patients observe therapists or MCI individuals with similar characteristics. Primary objectives include comparing AOT efficacy between these groups and a control group. Secondary objectives focus on upper limb functionality, daily activities, balance, cognition, and gait.

NCT ID: NCT05910047 Recruiting - Clinical trials for Age-associated Memory Impairment

Supplemental Hydrogen Plus PQQ for Mitochondrial Biomarkers and Brain Function in Elderly With Mild Cognitive Impairment

CALERIE
Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled double-blind parallel-group interventional trial is to evaluate the effects of dietary supplementation with molecular hydrogen and pyrroloquinoline quinone in elderly. The main questions it aims to answer are: (1) whether the supplementation affects biomarkers of mitochondrial function in serum, and (2) whether the supplementation affects cognition and brain metabolism. The participants will be subjected to take the dietary supplement during 6 weeks.

NCT ID: NCT05759910 Completed - Clinical trials for Age-associated Memory Impairment

Effect of BrainPhyt High Dose on Cognitive Function in Healthy Older Individuals

PHAEO-FOUR
Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate if BrainPhyt, a microalgae based ingredient may affect cognitive function parameters in older healthy individuals with evidence of age-related cognitive decline. In a double blind, randomized manner, 40 free living males and females between 55 to 75 years with age-associated memory decline will ingest Brainphyt supplement or Placebo for 12 weeks. Cognitive function battery will be realized after 4 and 12 weeks of supplementation.

NCT ID: NCT05462782 Terminated - Clinical trials for Age-associated Memory Impairment

TMS for Investigating Memory Facilitation

Start date: August 5, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals. For this purpose, we will apply TMS synchronized with a working memory (WM) task and assess its effects on cortical connectivity and memorization capacity by Magnetic Resonance Imaging (MRI) and WM task learning. This study will be carried out in an older population of healthy participants. We will use the study results to refine the task related PAS protocol towards enhancing memory performance and brain connectivity.

NCT ID: NCT01429103 Completed - Clinical trials for Alteration of Cognitive Function

Hormones and Cognition in the Menopausal Transition

Start date: May 2011
Phase: N/A
Study type: Observational

The purpose of this study is to determine if the menopausal transition is associated with subjective and objective cognitive declines that ameliorate in menopause. The investigators hypothesize that perimenopause is associated with both subjective memory complaints and objective declines in attentionally mediated cognitive tasks. The investigators also hypothesize that this is time-limited. The investigators predict that as women transition from early perimenopause to late perimenopause their performance on attentionally mediated and verbal memory tasks will decline, and that as they transition from late perimenopause to menopause, their performance will improve.

NCT ID: NCT00437983 Completed - Clinical trials for Age Associated Memory Impairment

The Efficacy of Phosphatidylserine-Omega3 in Elderly With Age Associated Memory Impairment

Start date: April 2007
Phase: Phase 4
Study type: Interventional

The primary objective of this trial is to assess the ability of an oral administration of Phosphatidylserine-Omega3 to improve attention and memory complaints in comparison to placebo in age associated memory impaired subjects.

NCT ID: NCT00355550 Completed - Clinical trials for Age-Associated Memory Impairment

Tricaprilin In Age-Associated Memory Impairment

Start date: July 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether tricaprilin, a compound that increases energy availability in the brain, improves memory in older adults with "normal" loss of memory abilities since early adult life.