Probiotics and Its Associated Factors on Aflatoxin Biomarkers

Aflatoxicosis Clinical Trial

Official title: Effect of Probiotics and Its Associated Factors on Aflatoxin Biomarkers Among Healthy Subjects in Serdang and Kajang, Selangor: A Twelve-week Intervention

Status Completed

Clinical Trial Summary

The study will be aimed to investigate the effect of probiotic intervention and its associated factors on aflatoxin biomarkers among healthy subjects in Serdang and Kajang, Selangor

Clinical Trial Description

The study will be a randomized, double-blind, placebo-controlled, parallel intervention that conducted for 12 weeks and followed-up for 4 weeks among healthy adults under living condition in Serdang and Kajang, Selangor. 164 subjects will be recruited for the intervention study, where 82 subjects will be randomly allocated to the probiotic or placebo group. Probiotic and placebo drinks (80 ml) will be prepared in the form of bottle. Placebo drink will have similar taste, colour, physical appearance, and nutritional value as probiotic drink but contain no LcS. Morning urine samples (15 ml), weight status, and dietary intake will be collected every two weeks from week 0 to week 12 and follow up until week 16 at community centre. Whereas, fasting blood samples (5 ml) and physical activity will be collected every four weeks for 16 weeks at the community centre. ;

Related Conditions & MeSH terms

• Aflatoxicosis

• NCT number: NCT03882294
• Study type: Interventional
• Source: Universiti Putra Malaysia
• Status: Completed
• Phase: N/A
• Start date: September 11, 2020
• Completion date: October 31, 2021