Adverse Drug Reaction Clinical Trial
Official title:
Pharmacogenetic Testing of Patients With Unwanted Adverse Drug Reactions or Therapy Failure
Genetic makeup of a patient influences the efficacy and safety profile of a drug. This study is to summarize individual cases, where Pharmacogenetics (PGx) has been applied during pharmaceutical care. The primary objective is the compilation of case reports, where pharmacogenetic testing is applied to determine the hereditable component of the patient's susceptibility to experience therapy failure and/or adverse drug reactions. The experience with the compiled cases will be basis for the development of a reliable standard of procedure for pharmacogenetic testing in the community pharmacy. The cases will be supplemented with information on additional Parameters reported in the literature to affect efficacy or safety of the respective drug.
Genetic makeup of a patient influences the efficacy and safety profile of a drug. This study is to summarize individual cases, where Pharmacogenetics (PGx) has been applied during pharmaceutical care. Health-related data of patients experiencing therapy failure (TF) or adverse drug reaction (ADR) is collected and will then be supplemented with pharmacogenetic testing during pharmaceutical care in a study pharmacy. The patient data (diagnoses, medications and results of pharmacogenetic testing) is harmonized in order to generate a compilation of case reports. The primary objective is the compilation of case reports, where pharmacogenetic testing is applied to determine the hereditable component of the patient's susceptibility to experience therapy failure and/or adverse drug reactions. The experience with the compiled cases will be basis for the development of a reliable standard of procedure for pharmacogenetic testing in the community pharmacy. The cases will be supplemented with information on additional Parameters reported in the literature to affect efficacy or safety of the respective drug. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Suspended |
NCT02559960 -
Post-marketing Safety Surveillance of Breviscapine Powder-Injection : a Registry Study
|
||
Completed |
NCT01946919 -
Post-Marketing Surveillance of the Cinepazide Maleate Injection: a Real World Study
|
||
Completed |
NCT01732302 -
Educational Intervention to Reduce Drug-related Hospitalizations in Elderly Primary Health Care Patients
|
N/A | |
Completed |
NCT05224804 -
Pharmacists' Knowledge and Attitudes About ADRs Reporting and Pharmacovigilance Practice in Egyptian Hospitals
|
||
Completed |
NCT02297126 -
A Prospective Trial to Assess Cost and Clinical Outcomes of a Clinical Pharmacogenomic Program
|
N/A | |
Completed |
NCT03093818 -
PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions
|
N/A | |
Not yet recruiting |
NCT04568668 -
Evaluating ActionADE in Reducing Adverse Drug Reactions
|
N/A | |
Recruiting |
NCT02012504 -
Antidepressant Monotherapy on Depressive and Anxiety Symptom in Chinese Patients
|
Phase 0 | |
Completed |
NCT01872520 -
Post-marketing Safety Surveillance of the Injection of DanShenDuoFenSuanYan A Real World Study
|
N/A | |
Completed |
NCT01467050 -
Prevention of Adverse Drug Events (ADEs) in Hospitalised Older Patients
|
Phase 4 | |
Completed |
NCT01679964 -
Sustained Virological Suppression and Improvement of Adverse Events of Switching to Raltegravir Study
|
Phase 4 | |
Completed |
NCT02094638 -
Post-Marketing Surveillance of the Tanreqing Injection: a Real World Study
|
N/A | |
Recruiting |
NCT01906710 -
the Pharmacy Intervention Team Hospital-based (PITH) for People Study: Effect on Clinical and Economic Outcomes
|
N/A | |
Completed |
NCT02888834 -
Serious Adverse Drug Reaction and Their Preventability
|
N/A | |
Completed |
NCT02838212 -
Adverse Drug Reactions With Fatal Outcome
|
N/A | |
Completed |
NCT02159209 -
The Drug Induced Renal Injury Consortium
|
N/A | |
Completed |
NCT02134587 -
Educational Intervention in Pharmacovigilance for Hospital Health Professionals
|
N/A | |
Completed |
NCT04553107 -
Reducing Costs by Deprescribing Medications
|
N/A | |
Recruiting |
NCT06219720 -
The Texas Interprofessional Pharmacogenomics (IPGx)
|
||
Recruiting |
NCT05508763 -
Personalised Therapeutics @LUMC
|