Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care

Adverse Drug Events Clinical Trial

— CMR  

Official title:

Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care: to Develop and Test a Community-based Medication Reconciliation Program and a Risk Prediction Model That Identifies High-risk Patient Groups

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01164137
• Other study ID #: CMPA#2026
• Status: Completed
• Phase: N/A
• First received: July 14, 2010
• Last updated: February 12, 2013
• Start date: November 2008
• Est. completion date: February 2013

Study information

• Verified date: February 2013
• Source: Westview Physician Collaborative
• Contact: n/a
• Is FDA regulated: No
• Health authority: Canada: Ethics Review Committee
• Study type: Interventional

Clinical Trial Summary

This initiative aims to decrease the risk of medication errors at the hospital-community interface as well as health system utilization following hospital discharge by implementing a pharmacist-led medication reconciliation in the patients' home within 72 hours of hospital discharge.

Description:

The goals of this initiative are to decrease the risk for medication errors at the hospital community interface of care, thus decreasing preventable adverse drug events and preventable drug-related health system utilization following hospital discharge. This initiative has four objectives that aim to:

1. Develop and test a community-based medication reconciliation process/intervention.

2. Design and conduct a randomized controlled trial to examine the impact of the intervention on post-discharge health services utilization by comparing a set of outcome variables between intervention and non-intervention groups.

3. Design a risk prediction model that helps identify patients discharged from in-patient care with the highest level of need for the intervention.

4. Determine whether a community-based medication reconciliation process/intervention adds risk reduction value to individuals who have undergone an in-hospital medication reconciliation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 156
• Est. completion date: February 2013
• Est. primary completion date: February 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients attending the WestView Health Centre Medicine/Family Health Unit with at least one medication at discharge.

Exclusion Criteria:

• First Nations persons

• Residents of continuing care or assisted living facilities

• Persons not residing in the Edmonton, AB, Canada region

• Persons who obtain a score of 19 or less on the Mini Mental State Examination (MMSE)

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research

Related Conditions & MeSH terms

• Adverse Drug Events
• Drug-Related Side Effects and Adverse Reactions

Intervention

Behavioral:
• Medication Reconciliation
A pharmacist-led home intervention conducted within 72 hours of hospital discharge aimed at correcting and identifying medication discrepancies.

Locations

Country	Name	City	State
Canada	WestView Health Centre	Stony Plain	Alberta

Sponsors (1)

Lead Sponsor	Collaborator
Westview Physician Collaborative

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Health Services Utilization 3 Months Following Hospital Discharge	Mean health services utilization 3 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.	3 Months	Yes
Primary	Health Services Utilization 6 Months Following Hospital Discharge	Mean health services utilization 6 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.	6 Months	Yes
Primary	Health Services Utilization 9 Months Following Hospital Discharge	Mean health services utilization 9 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.	9 Months	Yes
Primary	Health Services Utilization 12 Months Following Hospital Discharge	Mean health services utilization 12 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.	12 months	Yes
Primary	Health Services Utilization 18 Months Following Hospital Discharge	Mean health services utilization 18 months following hospital discharge. The specific health services utilization was re-admission to hospital, admission to home care, admission to long-term care and visits to emergency departments.	18 months	Yes